Brucellosis is a complicated and profoundly destructive disease. The bacterium has a myriad of species that can infect different animal populations, both domestic and wild, with many of the Brucella species capable of spreading to humans. It can also be difficult to identify clinically because in the absence of abortions or stillbirths, the disease causes no distinct clinical signs.
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USDA Agricultural Research Service researchers have developed an effective two-dose vaccine strategy for immunizing bison against brucellosis, but administering two separate inoculations to free ranging wild bison is a challenge.
- National Animal Disease Center





